Endocrine Abstracts

Introduction: Treatment of differentiated thyroid carcinoma (DTC) remains a challenge in the setting of locally advanced or metastatic disease refractory to radiodine (RAI) therapy. SELECT trial demonstrated that Lenvatinib improved progression free survival (PFS) comparing to placebo.Objective: Our aim is to report the efficacy and safety of lenvatinib in our population with aggressive DTC.Methods: We retrospectively reviewed the ...

Introduction: Thyroglobulin (Tg) measurement in needle washouts from fine-needle aspiration biopsies (FNA-Tg) increases the sensitivity of lymph node (LN) metastasis diagnosis in differentiated thyroid cancer (DTC). However, the cutoff value for FNA-Tg has not been clearly established and there are large differences between clinical studies, which hinders its interpretation. Our study aimed to investigate the optimal cutoff value of FNA-Tg and evaluate its utility in the diagn...

The relationship between periodontitis and diabetes mellitus (DM) is widely accepted. Several studies identified a greater incidence of periodontitis and an increase of its severity in diabetic patients, approximately threefold.In this study, we want to investigate the influence of type 2 DM (T2DM) in the development of periodontitis.Single center, randomized trial with 90 patients T2DM. Exclusion criteria: chronic renal disease (G...